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Bioinformatics Shared Resources

Sanford Burnham Prebys Medical Discovery Institute


Provided with target information, we can design a virtual screening strategy to help you select a small set of small molecules for you to use in biological testing for potential hits. Such a strategy is to cost effectively screen in silico a large database of commercially available drug-like molecules (on a million scale) that we have assembled. The strategy is based on either the target’s 3D structure or its known hits or on both. Furthermore, we can help improve your hits or leads by using molecule design tools.