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Bioinformatics Shared Resources
Sanford Burnham Prebys Medical Discovery Institute
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SOFTWARE
Software resources available at SanfordBurnham. Some of the software is maintained by IT on a server while other titles can be downloaded and used directly from your computer.
Below is a list of software organized by category:
Systems biology software and toold
We use: Ingenuity IPA, MetaCore (Thomson Reuters), NextBio, GeneSpring, TRANSFAC and Oncomine.
Statistical analysis software
We use: R, Partek, SAS and Excel data analysis toolpak
Available for use by other researchers at SBMRI: GraphPad Prizm (contact IT for install help) and Excel data analysis toolpak (see
here
how to load it)
DNA
Artemis
- a desktop DNA sequence viewer and annotation tool (PC and Mac).
Staden Package
Package for DNA sequence preprocessing, assembly and editing.
RepeatMasker
is a program that screens DNA sequences for interspersed repeats and low complexity DNA sequences.
Oligo
is a desktop program for primer design and analysis (PC and Mac).
Protein
Dotter
Creates dot-plot similarity matrix between DNA-DNA, protein-protein and DNA-protein sequences
Blast
A suite of programs for searching DNA/protein sequence databases
Alignment
T-Coffee
Multiple sequence alignment program for both protein and DNA.
Phylogeny
MrBayes
Estimate phyolgenetic relationships using Bayesian statistics.
ATV
Java tool for the visualization of annotated phylogenetic trees.
3D Molecular Structure
PyMol
Visually sophisticated tool for creating publication or presentation quality 3D images of molecular structures.
RasMol
Simple but powerful desktop structure visualization and annotation tool. Runs on PC, Mac, Unix.
Microarray and Gene Expression
GeneSpring
BioConductor
GenePattern
Proteomics
GenePattern
Mascot
Trans-Proteomic Pipeline
Crystallography
ccp4
CNSsolve
HKL
O
Resolve
Electron density map improvement
SHARP/autoSHARP
Phasing program for multiple wavelenth data sets
Shelx97
Structure determination suite
Solve
Automated structure determination from MIR, SAD or MAD data
XDS
x-ray detector sofware for monochromatic data
NMR
NMRpipe
provides facilities for conversion and processing of 1D-4D NMR spectra
NMRViewJ
A program for the visualization and analysis of NMR datasets